(2024)
Modeling of intravenous caspofungin administration using an intestine-on-chip reveals altered Candida albicans microcolonies and pathogenicity.
Biomaterials 307,
122525.
Publications
(2024)
The hyphal-specific toxin candidalysin promotes fungal gut commensalism.
Nature
[Epub ahead of print]
(2024)
Secretion of the fungal toxin candidalysin is dependent on conserved precursor peptide sequences.
Nat Microbiol 9(3),
669-683.
(2024)
Hyphal-associated protein expression is crucial for Candida albicans-induced eicosanoid biosynthesis in immune cells.
Eur J Immunol ,
e2350743.
(2024)
Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκBmediated barrier protection.
Plos Pathogens 20(3),
e1012031.
(2024)
Nanobody-mediated neutralization of candidalysin prevents epithelial damage and inflammatory responses that drive vulvovaginal candidiasis pathogenesis.
mBio ,
e0340923.
(2023)
Ncs2* mediates in vivo virulence of pathogenic yeast through sulphur modification of cytoplasmic transfer RNA.
Nucleic Acids Res 51(15),
8133-8149.
(2023)
High-throughput profiling of Candida auris isolates reveals clade-specific metabolic differences.
Microbiol Spectr 11(3),
e0049823.
(2023)
Respiration supports intraphagosomal filamentation and escape of Candida albicans from macrophages.
mBio 14(6),
e0274523.
(2023)
Ecological niche-inspired genome mining leads to the discovery of crop-protecting nonribosomal lipopeptides featuring a transient amino acid building block.
J Am Chem Soc 145(4),
2342-2353.