Mikrobielle Pathogenitätsmechanismen

Wu Y, Du S, Bimler LH, Mauk KE, Lortal L, Kichik N, Griffiths JS, Osicka R, Song L, Polsky K, Kasper L, Sebo P, Weatherhead J, Knight JM, Kheradmand F, Zheng H, Richardson JP, Hube B, Naglik JR, Corry DB (2023) Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis. Cell Rep 42(10), 113240.

Allert S, Schulz D, Kämmer P, Großmann P, Wolf T, Schäuble S, Panagiotou G, Brunke S, Hube B (2022) From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris. Virulence 13(1), 191-214.

Alonso-Roman R, Last A, Mirhakkak MH, Sprague JL, Möller L, Großmann P, Graf K, Gratz R, Mogavero S, Vylkova S, Panagiotou G, Schäuble S, Hube B, Gresnigt MS (2022) Lactobacillus rhamnosus colonisation antagonizes Candida albicans by forcing metabolic adaptations that compromise pathogenicity. Nat Commun 13(1), 3192.

Declas N, Maynard JRJ, Menin L, Gasilova N, Götze S, Sprague JL, Stallforth P, Matile S, Waser J^* (2022) Tyrosine bioconjugation with hypervalent iodine. Chem Sci 13(43), 12808-12817.

Gómez AC, Lyons T, Mamat U, Yero D, Bravo M, Daura X, Elshafee O, Brunke S, Gahan CGM, O'Driscoll M, Gibert I, O'Sullivan TP (2022) Synthesis and evaluation of novel furanones as biofilm inhibitors in opportunistic human pathogens. Eur J Med Chem 242, 114678.

Lapaquette P, Ducreux A, Basmaciyan L, Paradis T, Bon F, Bataille A, Winckler P, Hube B, d'Enfert C, Esclatine A, Dubus E, Bringer MA, Morel E, Dalle F (2022) Membrane protective role of autophagic machinery during infection of epithelial cells by Candida albicans. Gut Microbes 14(1), 2004798.

Li XV, Leonardi I, Putzel GG, Semon A, Fiers WD, Kusakabe T, Lin WY, Gao IH, Doron I, Gutierrez-Guerrero A, DeCelie MB, Carriche GM, Mesko M, Yang C, Naglik JR, Hube B, Scherl EJ, Iliev ID (2022) Immune regulation by fungal strain diversity in inflammatory bowel disease. Nature 603(7902), 672-678.

Mogavero S, Höfs S, Lauer AN, Müller R, Brunke S, Allert S, Gerwien F, Groth S, Dolk E, Wilson D, Gutsmann T, Hube B (2022) Candidalysin is the hemolytic factor of Candida albicans. Toxins (Basel) 14(12), 874.

Richardson JP, Brown R, Kichik N, Lee S, Priest E, Mogavero S, Maufrais C, Wickramasinghe DN, Tsavou A, Kotowicz NK, Hepworth OW, Gallego-Cortés A, Ponde NO, Ho J, Moyes DL, Wilson D, D'Enfert C, Hube B, Naglik JR (2022) Candidalysins are a new family of cytolytic fungal peptide toxins. mBio 13(1), e0351021.

Siscar-Lewin S, Hube B, Brunke S (2022) Emergence and evolution of virulence in human pathogenic fungi. Trends Microbiol 30(7), 693-704. (Review)