Interaction of MAIT cells with moulds

Mucosal-associated invariant T (MAIT) cells are innate-like T cells with a specific invariant T cell receptor (TCRVa7.2) which recognizes riboflavin-metabolites presented by MR1 on antigen-presenting cells. The activity against bacteria, yeasts and viruses has already been shown. Our group looks at the interaction of MAIT cells with mould species. These projects include Aspergillus spp. as well as Mucorales and investigate MAIT cells from healthy donors as well as patients.

Activation of human MAIT cells by A. fumigatus.
Members
Susanne Jahreis

Dr. Susanne Jahreis

Post-doc

Phone: +49 3641 532-1081 Email: susanne.jahreis@leibniz-hki.de

Ava Kiesewetter

Ava Kiesewetter

technical assistant

Phone: +49 3641 532-1578 Email: ava.kiesewetter@leibniz-hki.de

Carolin Arnsmeyer

Student assistant

Email: Carolin.Arnsmeyer@uni-jena.de

Noreen Schuck

Noreen Schuck

Student assistant