Curriculum vitae

Main Research Areas
  • Synthesis and Derivatisation of Natural Products
  • Synthetic Method Development
  • Medicinal Chemistry
  • Target Identification
Professional Career
2016- PhD Student Hans-Knöll-Institute
2013-2016   Scientific Assistent in the Research Group of Prof. Riedl (ZHAW)
2011-2013 Master Studies Life Sciences (ZHAW)
2008-20011 Bachelor Studies Chemistry - Zürcher Hochschule für Angewandte Wissenschaften (ZHAW)
2005-2008 Apprenticeship: Chemical Laboratory Assistent



Publications

Bissell AU, Rautschek J, Hoefgen S, Raguž L, Mattern DJ, Saeed N, Janevska S, Jojić K, Huang Y, Kufs JE, Herboeck B, Guo H, Hillmann F, Beemelmanns C, Valiante V (2022) Biosynthesis of the Sphingolipid Inhibitors Sphingofungins in Filamentous Fungi Requires Aminomalonate as a Metabolic Precursor. ACS Chem Biol [Epub ahead of print]
Brand M, Wang L, Agnello S, Gazzola S, Gall FM, Raguž L, Kaiser M, Schmidt RS, Ritschl A, Jelk J, Hemphill A, Mäser P, Bütikofer P, Adams M, Riedl R (2021) Antiprotozoal structure-activity relationships of synthetic leucinostatin derivatives and elucidation of their mode of action. Angew Chem Int Ed 60(28), 15613-15621.
Leichnitz D, Peng CC, Raguž L, Rutaganira FUN, Jautzus T, Regestein L, King N, Beemelmanns C (2021) Structural and functional analysis of bacterial sulfonosphingolipids and rosette-inducing factor 2 (RIF-2) by mass spectrometry-guided isolation and total synthesis Chemistry [Accepted]
Raguž L, Peng CC, Kaiser M, Görls H, Beemelmanns C* (2021) A modular approach to the antifungal Sphingofungin family: Concise total synthesis of Sphingofungin A and C. Angew Chem Int Ed [Accepted]
Roman D, Raguž L, Keiff F, Meyer F, Barthels F, Schirmeister T, Kloss F, Beemelmanns C (2020) Modular solid-phase synthesis of antiprotozoal barnesin derivatives. Org Lett 22(10), 3744-3748.
Raguz L, Beemelmanns C (2019) Ursprung und Funktionen der Sphingolipide. Nachrichten aus der Chemie 67(2), 66-70. (Review)
Guo H, Schmidt A, Stephan P, Raguž L, Braga D, Kaiser M, Dahse HM, Weigel C, Lackner G, Beemelmanns C (2018) Precursor-directed diversification of cyclic tetrapeptidic pseudoxylallemycins. ChemBioChem 19(21), 2307-2311.
Rischer M, Raguz L, Guo H, Keiff F, Diekert G, Goris T, Beemelmanns C (2018) Biosynthesis, synthesis and activities of barnesin A, a NRPS-PKS hybrid produced by an anaerobic Epsilonproteobacterium. ACS Chem Biol 13(8), 1990-1995.
Leichnitz D, Raguž L, Beemelmanns C (2017) Total synthesis and functional analysis of microbial signalling molecules. Chem Soc Rev 46(20), 6330-6344. (Review)
Chellat MF, Raguž L, Riedl R (2016) Targeting Antibiotic Resistance. Angew Chem Int Ed Engl 55(23), 6600-6626.

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